Introduction

Product Features

Indications

Biopsy Technique

Implantation Technique

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BioSeed^®-C, the autologous 3-dimensional chondrocyte graft with a unique shape for primary mechanical stability. Used successfully since 2002 to treat degenerative and traumatic articular cartilage defects and proven with 5 years clinical follow-up in the treatment of osteoarthritis.

• Patented, stable 3D matrix
• Unique, secure fixation by arthroscopy or arthrotomy (e.g. with absorbable nails)
• Stable form and shape
• Treatment of single and multiple, traumatic and degenerative defects with sub-optimal surrounding cartilage measuring less than 10 cm²
• Sizes: 30 mm x 20 mm x 2 mm; 30 mm x 20 mm x 1.1 mm; 30 mm x 30 mm x 1.1 mm; 50 mm x 20 mm x 1.1 mm
• 28.8 millions cells per unit
• GMP manufacturing
• Flexible scheduling for transplantation
• Delivered throughout Europe
• Implantation 4.5 weeks after cartilage biopsy
• More than 3000 patients successfully treated

Thanks to autologous chondrocyte transplantation with a stable 3D matrix, knee injuries (femoral condyle, tibia plateau, patella) can be treated with the patient’s own cells.

BioSeed^®-C consists of two components: a polymer carrier fleece which forms the framework structure and a biological “glue” which fixes the homogenously distributed chondrocytes in the carrier fleece. This combination provides the chondrocytes with an ideal three-dimensional environment which stimulates them to redifferentiate and thus assume their original morphology and function.

As a result, BioSeed^®-C is mechanically stable, supple, flexible and can be cut to fit the size of the defect.

BioSeed^®-C is produced in a GMP laboratory according to strict manufacturing criteria.

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